MULTIFUNCTIONAL WOUND HEALING DEVICE WITH CONTROLLED DRUG DELIVERY AND WOUND HEALTH MONITORING FUNCTIONALITIES FOR REAL-TIME MANAGEMENT OF WOUNDS / (Record no. 610647)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02753nam a22001577a 4500 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Mir, Mariam |
| 245 ## - TITLE STATEMENT | |
| Title | MULTIFUNCTIONAL WOUND HEALING DEVICE WITH CONTROLLED DRUG DELIVERY AND WOUND HEALTH MONITORING FUNCTIONALITIES FOR REAL-TIME MANAGEMENT OF WOUNDS / |
| Statement of responsibility, etc. | Mariam Mir |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Islamabad : |
| Name of producer, publisher, distributor, manufacturer | SMME- NUST; |
| Date of production, publication, distribution, manufacture, or copyright notice | 2021. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 265p. |
| Other physical details | Soft Copy |
| Dimensions | 30cm |
| 500 ## - GENERAL NOTE | |
| General note | Wound management has been efficiently handled by the development of a smart<br/>bi-functional real time modular system that combines and synchronizes<br/>quantitative assessment of wound health with wearable drug dispenser for<br/>controlled and desired drug dispensation for specific patient demand. The wound<br/>monitoring system is composed of a biocompatible, planar, point of care and<br/>flexible wearable patch comprising of a pH sensor array that can easily conform<br/>to body contours and efficiently provide a spatial map of pH levels for different<br/>areas of the wound, since variations in pH are indicative of physiological<br/>alteration such as inflammation and tumor growth. The design of pH sensor array<br/>is dependent on electrode density, which is a function of both the optimized size<br/>and separation of electrodes. Based on the final electrode density, an optimized<br/>design of the pH sensor array has been developed, using copper tracts on a<br/>polyimide substrate and a hydrophilic pH responsive hydrogel as the pH sensitive<br/>component. The treatment module comprising of the wearable drug dispenser has<br/>been developed using the concept of an electronically controlled drug delivery<br/>through a haptic vibratory mechanism that is precisely controlled and tuned for<br/>drug release to affected areas. In addition, an environmentally triggered, pH<br/>responsive hydrogel based drug delivery system has also been developed in<br/>tandem, as a comparison with the electronically controlled system. The individual<br/>components of the proposed wound management system have been extensively<br/>tested for physical, chemical and performance related characteristics;<br/>subsequently, the systems have been used in the in-vivo setting to establish a<br/>baseline for future clinical testing and usability. Our observations and results<br/>suggest that the both the diagnostic and treatment components of the wound<br/>management system have the potential to mark an improvement in the current<br/>situation for wound management in hospital settings. The development of this<br/>extensively tested prototype system clears the way for further clinical studies to<br/>be undertaken in this regard. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | PhD in Biomedical Sciences |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Supervisor : Dr. Murtaza Najabat Ali |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://10.250.8.41:8080/xmlui/handle/123456789/27907">http://10.250.8.41:8080/xmlui/handle/123456789/27907</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Thesis |
| Withdrawn status | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Barcode | Koha item type |
|---|---|---|---|---|---|---|---|
| School of Mechanical & Manufacturing Engineering (SMME) | School of Mechanical & Manufacturing Engineering (SMME) | E-Books | 07/30/2024 | 610 | SMME-Phd-12 | Thesis |