Silymarin silver nanoparticles loaded biomimetic coating for titanium implants / (Record no. 611747)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02263nam a22001577a 4500 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Shahid ,Eman |
| 245 ## - TITLE STATEMENT | |
| Title | Silymarin silver nanoparticles loaded biomimetic coating for titanium implants / |
| Statement of responsibility, etc. | Eman Shahid |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Islamabad: |
| Name of producer, publisher, distributor, manufacturer | SMME- NUST. |
| Date of production, publication, distribution, manufacture, or copyright notice | 2024. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 79p. ; |
| Other physical details | Soft Copy, |
| Dimensions | 30cm. |
| 500 ## - GENERAL NOTE | |
| General note | Titanium is most frequently utilized for making orthopedic and orthodontic implants.<br/>Titanium implants are most extensively used because of their anti-corrosive properties,<br/>having high success rate. Despite high success rate, there still are number of cases in which<br/>implant rejection is observed. Surface modification techniques for improving surface<br/>properties, surface roughness and their interaction with biological environment has been<br/>explored to overcome the risk of implant associated infections. This research aims at<br/>designing a silymarin silver nanoparticles loaded biomimetic coating for titanium implants<br/>which results in implants having improved anti-biofilm activity, improved osseointegration<br/>and biocompatibility. Green synthesis approach is employed for silver nanoparticles<br/>synthesis using Silybum marianum L. plant extract, which is rich in free hydroxyl groups<br/>which can reduce Ag+ ions into Ag nanoparticles. Titanium implants are bio-inert they<br/>cannot interact with the bone to form a bond that limits their osseointegration. Bone like<br/>apatite coating on the titanium surface is being explored for improving osseointegration<br/>potential of the surface. The potential of silymarin as a reducing agent is confirmed by the<br/>UV spectrometry, XRD, FTIR, SEM and zeta potential analysis of silver nanoparticle.<br/>Anti-biofilm crystal violet assay confirmed the anti-biofilm potential of the coated titanium<br/>discs. SEM analysis showed uniform coating of calcium phosphate and silver nanoparticles<br/>on the titanium surface. Decrease in contact angle of the coated titanium disc confirmed<br/>increase in the hydrophilicity of the titanium disc, which denotes increase in the<br/>osseointegration of titanium discs. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MS Biomedical Sciences (BMS) |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Supervisor: Dr. Nosheen Fatima Rana |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://10.250.8.41:8080/xmlui/handle/123456789/46684">http://10.250.8.41:8080/xmlui/handle/123456789/46684</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Thesis |
| Withdrawn status | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Barcode | Koha item type |
|---|---|---|---|---|---|---|---|
| School of Mechanical & Manufacturing Engineering (SMME) | School of Mechanical & Manufacturing Engineering (SMME) | E-Books | 09/23/2024 | 610 | SMME-TH-1068 | Thesis |