| 000 -LEADER |
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| fixed length control field |
03426nam a22001577a 4500 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
610 |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Ali, Zumair |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
HemoSys: An Integrated Framework for Hemodialysis Machine Operation, Real-Time Monitoring, Data Management and Predictive Modeling for Patient Safety / |
| Statement of responsibility, etc. |
Zumair Ali |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Islamabad : |
| Name of producer, publisher, distributor, manufacturer |
SMME- NUST; |
| Date of production, publication, distribution, manufacture, or copyright notice |
2025 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
91p. |
| Other physical details |
Soft Copy |
| Dimensions |
30cm |
| 500 ## - GENERAL NOTE |
|---|
| General note |
Hemodialysis is of paramount importance to patients who undergo renal failure and kidney<br/>dysfunction. It requires precise control and monitoring to ensure the safety of the patient<br/>and the efficacy of the process. HemoSys is a high-end framework for the revolutionized<br/>operation of hemodialysis machines by real-time monitoring, data management, and<br/>predictive modeling. The system will answer all diverse needs related to hemodialysis<br/>treatment. It has highly developed peristaltic pumps and syringe pump controllers to<br/>manage blood and dialysate flows, assuring cautious fluid management. Advanced sensors<br/>are integrated for real-time monitoring of pressure, temperature, and bubble formation that<br/>support the continuous tracking of critical parameters of treatment. The Graphical User<br/>Interface enables users to easily interact with real-time visualization of sensor data and<br/>offers intuitive controls for the hemodialysis operation. Other than the operational<br/>capacities, several strong data management features are hosted by HemoSys. All patients,<br/>operators, physicians, and sessions data get stored in a MySQL database, thereby providing<br/>an efficient retrieval and update of data. The system also offers export options to PDF and<br/>excel, thereby enhancing data accessibility and usability. One of the unique features of<br/>HemoSys is predictive modeling incorporated in the software framework. In this research,<br/>Random Forest, XG Boost, Cat Boost and Light GBM were employed, trained on the<br/>hemodialysis patient data of 10352 dialysis sessions, to predict the adequacy of<br/>hemodialysis session based on all the relative variables instead of only relying on few<br/>variables like Kt/V, Ultrafiltration etc. These models were trained using RFE and PCA<br/>methods to find the best feature classification/reduction technique for adequacy prediction.xvii<br/>The paired t-test indicated that there was a significant difference between outcome<br/>parameters for both in feature reduction techniques and RFE was proved better. And under<br/>RFE, the paired t-test was employed on performance matrix (accuracy, precision, F1 score,<br/>recall and AUROC) of all the models and there was significant difference between two<br/>combinations (RF, XG Boost) and (RF, LGBM). XG Boost and LGBM performed best<br/>based on outcome parameters (0.9932, 0.9949, 0.0.9949, 0.9949, 0.9924) and (0.9931,<br/>0.9949, 0.9952, 0.9951, 0.9916) respectively. HemoSys is the step forward to introduce<br/>predictive modelling in dialysis technology to provide operators with significant insight to<br/>change session parameters for better patient outcomes. This approach increases safety,<br/>efficiency, and effectiveness regarding hemodialysis treatment and is therefore a very<br/>promising solution for healthcare providers, patients, and all stakehold |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
MS Biomedical Engineering (BME) |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Supervisor : Dr. Muhammad Asim Waris |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="http://10.250.8.41:8080/xmlui/handle/123456789/49123">http://10.250.8.41:8080/xmlui/handle/123456789/49123</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Koha item type |
Thesis |
