Advanced nanocarriers for skin diseases / (Record no. 615165)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01938nam a22001577a 4500 |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Khan, Rida Khalid |
| 245 ## - TITLE STATEMENT | |
| Title | Advanced nanocarriers for skin diseases / |
| Statement of responsibility, etc. | Rida Khalid Khan |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Islamabad : |
| Name of producer, publisher, distributor, manufacturer | SMME- NUST; |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 68p. |
| Other physical details | Soft Copy |
| Dimensions | 30cm |
| 500 ## - GENERAL NOTE | |
| General note | The development and evaluation of an advanced nanocarrier hydrogel system designed to address<br/>the major barriers in diabetic wound healing, specifically targeting chronic inflammation,<br/>oxidative stress, bacterial infection, and impaired angiogenesis. This therapeutic system integrates<br/>cerium oxide nanoparticles (CeO₂), metal-organic frameworks (MOFs), and a chitosan-gelatin<br/>hydrogel platform to create a multifunctional wound dressing. CeO₂ nanoparticles provide strong<br/>antioxidant and antibacterial activity, MOFs enable controlled drug release and add antimicrobial<br/>properties, while the chitosan-gelatin hydrogel ensures biocompatibility, moisture retention, and<br/>accelerated tissue repair. Comprehensive characterization, including Raman spectroscopy, FTIR,<br/>UV-Vis, EDX analysis, and optical microscopy, confirmed successful synthesis, structural<br/>integrity, and the presence of desired functional groups. Biological assays demonstrated superior<br/>antibacterial and antibiofilm performance of the CeZn-Gel composite against E. coli and S. aureus,<br/>surpassing individual system components and controls. The integrated approach not only enhances<br/>wound healing outcomes but also reduces infection and inflammation, with significant potential<br/>for improving patient quality of life in chronic wound care. Future work will focus on optimizing<br/>formulation and advancing toward clinical testing for broader therapeutic impact. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MS Biomedical Sciences (BMS) |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Supervisor : Dr. Nosheen Fatima |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://10.250.8.41:8080/xmlui/handle/123456789/55616">http://10.250.8.41:8080/xmlui/handle/123456789/55616</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Thesis |
| Withdrawn status | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Barcode | Koha item type |
|---|---|---|---|---|---|---|---|
| School of Mechanical & Manufacturing Engineering (SMME) | School of Mechanical & Manufacturing Engineering (SMME) | E-Books | 10/14/2025 | 610 | SMME-TH-1189 | Thesis |