Customization of 3D-Printed Knee Implants: Design Optimization and Lattice Structure Integration fo Enhanced Performance / (Record no. 615712)

000 -LEADER
fixed length control field 02614nam a22001577a 4500
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Ahmad, Fatima Ajaz
245 ## - TITLE STATEMENT
Title Customization of 3D-Printed Knee Implants: Design Optimization and Lattice Structure Integration fo Enhanced Performance /
Statement of responsibility, etc. Fatima Ajaz Ahmad
264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Islamabad :
Name of producer, publisher, distributor, manufacturer SMME- NUST;
Date of production, publication, distribution, manufacture, or copyright notice 2025.
300 ## - PHYSICAL DESCRIPTION
Extent 93p.
Other physical details Soft Copy
Dimensions 30cm
500 ## - GENERAL NOTE
General note Total Knee Replacement (TKR) surgeries are becoming increasingly common globally as<br/>an effective measure to counter knee arthritis. Total knee replacement implants are very<br/>advantageous in a sense that they offer 99% success rate to patients. This thesis presents<br/>the design, simulation and additive manufacturing of a patient specific, Functionally<br/>Graded Lattice Structure (FGLS) knee implant in Ti 6Al-4V alloy with specific reference<br/>to the healthcare situation in Pakistan. This was to explore the local manufacturing facilities<br/>of Pakistan as all knee implants are imported from abroad.<br/>The strategy involved a high degree of workflow consisting of Computer-Aided Design<br/>(CAD), finite element analysis (FEA), and topology optimization using nTopology to<br/>create Gyroid-based lattice work. The structures were to resemble the trabecular bone<br/>structure to ensure that stiffness discrepancies were minimized. This helped counter only<br/>one drawback of solid knee implants, stress shielding.<br/>The simulations of the physiological loading conditions (static and cyclic) demonstrated a<br/>Von Mises peak of 620.45 Mpa and safety factor of 12.66 on the average and unlimited<br/>predicted life of fatigue of over 10^7 cycles. The use of FGLS was effective in making the<br/>weight of 490 g to 292, leading to a 40 percent weight reduction, with no structural integrity<br/>lost. Selective Laser Melding (SLM) was used to fabricate the implant and the heat<br/>treatment allowed stress relieving of the additively manufactured implant.<br/>Compressive testing was also mechanically vindicated to be on an of average 95.02 kN<br/>with little variation and Micro-CT scanning confirmed high dimensional fidelity and<br/>showed internal lattice geometries without defects. According to this research, SLM<br/>produced FGLS implants usage has proven to be an option to traditional prosthetics, which<br/>is mechanically stable, biologically desirable, and cost-effective, and has a bright future of<br/>being a locally manufactured orthopedics product.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MS Biomedical Engineering (BME)
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Supervisor : Dr. Nabeel Anwar
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://10.250.8.41:8080/xmlui/handle/123456789/57064">http://10.250.8.41:8080/xmlui/handle/123456789/57064</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Thesis
Holdings
Withdrawn status Permanent Location Current Location Shelving location Date acquired Full call number Barcode Koha item type
  School of Mechanical & Manufacturing Engineering (SMME) School of Mechanical & Manufacturing Engineering (SMME) E-Books 12/30/2025 610 SMME-TH-1202 Thesis
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