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Vaccination was the only method available to stop the COVID-19 epidemic once it had
started. There is skepticism about the efficacy and safety of current COVID-19
vaccination around the world. Because glycemic alterations have been observed after
immunization, there were significant worries regarding post-vaccination unfavorable
consequences in the diabetic community. The purpose of this study is to examine the
adverse effects of post-COVID-19 vaccination in diabetic and non-diabetic subjects
who received various types of vaccinations, including inactivated viral vaccines
(Sinopharm and Sinovac), RNA-based vaccines (Moderna and Pfizer), and nonreplicating-viral vaccines (AstraZeneca and Casino bio). This study aims to investigate
the concomitant side effects caused by different COVID-19 vaccines in diabetic and
non-diabetic populations by questionnaire, interviews, and analysis of blood samples
for different biomarkers. Data collected was analyzed using IBM-SPSS by applying an
independent sample T-test, chi-square test, and binary logistic regression. Most of the
side effects were reported within the age group 31-40 and 41-50. There is no significant
difference in side effects after vaccination in diabetic and non-diabetic individuals. The
glycemic imbalance was seen high in individuals vaccinated with RNA-based vaccine
with n=27(31.2%) reporting high blood sugar levels. Concluded that these vaccines are
safe for diabetic individuals but keeping results in view RNA-based vaccines should be
administered with blood glycemic levels in check.