Kamran, Muhammad Hamza  <br/><br/>
Detection of Hypochromic Erythrocytes in Blood Smear by using Edge Contours of Cells as Trigonometric Projections / 
Muhammad Hamza Kamran 
 - 75p.  Soft Copy  30 
<br/><br/> Hypochromic erythrocytes are red blood cells (RBC) with central pallor larger than<br/>normal and hence overall appears paler. This paleness is due to lack of hemoglobin<br/>responsible for carrying oxygen and giving red color to erythrocytes. Hypochromic erythrocytes are commonly associated with iron deficiency anemia. Anemia is manually<br/>diagnosed through peripheral blood smear (PBS) test. The monolayer of blood smear<br/>is observed by pathologist as its the only region with erythrocytes is observably visible.<br/>PBS test is the gold standard in analyzing blood cells yet its time consuming tedious<br/>task. Automated techniques are applied to analyze the cells but did not properly addressed the overlapped anemia cells. Overlapped cells are also overlooked by pathologist<br/>as well in manual PBS test. Trigonometric projection is mapped from the detected enclosed edges of cells from microscopic images. Prior to edge detection, the images are<br/>color processed to remove all leukocytes and platelets leaving only Erythrocytes and<br/>later eroded and dilated to remove small residue preserving the cells. The proposed<br/>method performance metric is 95.27 %, 82.45% and 88.39% for precision, recall and F1<br/>score respectively. 
<br/><br/><label>Subjects--Topical Terms: </label><br/>MS Biomedical Engineering (BME)      
<br/><br/><label>Dewey Class. No.: </label>610