NUST Institutions Library Catalogue Search for 'kw,wrdl: (su-br:"Tissues.")'

Deformable Image Registration for Neurosurgical Procedures /

By Ahmad, Sahar. Rawalpindi, MCS (NUST), 2016 . xv, 111 p

Place Hold on Deformable Image Registration for Neurosurgical Procedures /

Fermentation microbiology and biotechnology /

Boca Raton, FL : Taylor & Francis/CRC Press, 2012 . xix, 535 p. : 26 cm.. 9781439855799 (hardcover : alk. paper)

Place Hold on Fermentation microbiology and biotechnology /

TH-MS-Identification of Intergration Sites of Mouse Mammary Tumor Virus in Human Breast Cancer Tissues

By Talha Bin Rahat-sup-Dr. Hajira Sadia . Islamabad ASAB NUST 2014 . xiv, 78 P

Place Hold on TH-MS-Identification of Intergration Sites of Mouse Mammary Tumor Virus in Human Breast Cancer Tissues

Brain Tumor Detection and Localization using MRI Images /

By Asadullah, Muhammad . . 75 p

Place Hold on Brain Tumor Detection and Localization using MRI Images /

Early Diagnosis of AD by Detecting Amyloid-Beta in the Retina of AD-Induced Mice Using IR Spectroscopy /

By Waheed, Zuha. . 66p. 30cm.

Place Hold on Early Diagnosis of AD by Detecting Amyloid-Beta in the Retina of AD-Induced Mice Using IR Spectroscopy /

Effectivity of Rutin-bound Carbon dots in preventing the aggregation of Amyloid beta /

By Noor Afza. . 78p. , According to the World Health Organization up to 55 million people have dementia resulting in concerning socio-economic implications. About 60-80% cases of dementia are associated with Alzheimer's disease. With all the advances in medicine, there still is no cure. Blood-brain barrier monitors the entry and exit of nutrients and molecules which makes it difficult for various drugs and therapeutic molecules to cross it. Carbon dots are made from glucose to overcome the BBB. Rutin is a naturally existing flavonoid extracted from plants and has therapeutic effects in neuroprotection. This study aims to improve the effectiveness of rutin combined with targeted delivery of carbon dots. Carbon dots were loaded with Rutin to make CD-Rutin, a nano-sized combination with a targeted drug. FTIR, UV-IR, and SEM analysis have produced positive results regarding the doping of CDs with Rutin. Administration of CD-Rutin was done in AD-like rat models at eight to twelve months of age. Alzheimer's was induced in rats with Aluminum Chloride and D-galactose through IP administration for two weeks. Behavioral tests were performed to check the progression of the disease. In silico analysis was also done to check ligand-protein interaction to check variation in the binding of Aβ isoforms with Rutin. Afterward, a single injection of CD-Rutin (10 mg/kg) was given intraperitoneally as well. Behavioral testing was done after the administration of the drug. Characterization techniques revealed the successful formation of CDs and subsequent loading of Rutin onto the CDs resulting in a CD-Rutin combination. In silico analysis provided strong binding affinities of Rutin with Aβ isoforms affirming Rutin as a favorable treatment to target amyloid aggregates. 3D configuration showed binding of Rutin with hydrophobic domains of protein oligomers Behavioral testing provided significant difference in the treated group with better memory retention and performance in activities involved in behavioral testing. After behavioral testing, rats were dissected for molecular analysis including H&E to assess cell degeneration and Thioflavin T staining to assess amyloid aggregates in the brain tissues. Results provided positive data in terms of cell count in the cortex. Overall results suggest that memory impairment and cognitive abilities were significantly improved after injections. The results demonstrate the positive therapeutic potential of CD-Rutin in Alzheimer's treatment. 30cm.

Place Hold on Effectivity of Rutin-bound Carbon dots in preventing the aggregation of Amyloid beta /

Development of Reinforced Metal Tubing for Vascular Applications /

By Arshad, Aimen . . 53p , Coronary artery diseases remain one of the leading causes of mortality, with the incidence of death rate being 20% in Pakistan. The disease causes deposition of plaque on the lumen of the blood vessels that narrow the coronary arteries (blood) hindering the blood flow to the heart and rest of the tissues. The treatment procedure of the disease involves delivering the expandable device (balloon/stent) to the target region. Guide catheters plays a crucial role for the advancement of these treatment devices (stent/balloon). Guide catheters are hollow tubular structures of 100-110 cm in length, which are required to provide support, and facilitate the delivery of the stent/balloon at the target region. The guide catheter is made to enter the body via the wrist/femoral artery. From here, it traverses all the way to the heart while passing through blood vessels of varying diameter, and a tortuous anatomy of the body. In fact, the pathway of the guide catheter is not a straight, rather a curved path. It is important for the guide catheter to have certain mechanical characteristics to reach the heart without causing any vascular trauma. The performance of the guide catheter heavily relies on its braided shaft, and the outer jacket. Spontaneous movement of the catheter due to its instability, coronary dissections due to a high push force, and arterial spasms resulting from the friction are a few common problems of guide catheters used commercially. The current research is focused on catering these challenges by optimizing the pitch of the braided shaft and jacketing the shaft with a polymer unique to commercial catheters. In order to find the best guide catheter to meet the challenges presented in the literature, three guide catheters of varying pitch were designed, and coated with a polyimide jacket material. The protypes were tested for performance under mechanical, and physically testing and the candidate performing the best was selected. The guide catheter that performed the best in providing the longitudinal stiffness, reducing the friction, and decreasing the push force was chosen, and bench tested. 30cm.

Place Hold on Development of Reinforced Metal Tubing for Vascular Applications /

Fixed-Value MBLL based Cognitive Hemodynamic response assessment using P-fNIRS system: Applications to Deep Learning Brain Machine Interface (BMI) /

By Asgher,Umer . . 172p. , Humans in the modern systems not only interact with other humans but also have to interact with intelligent machines, robots in form of cyber physical systems to collaborate in order to carry out different tasks in real working environment. The modern Industrial system comprises of humans, machines, and cyber systems with a collective aim of optimized industrial manufacturing objectives, human factors, and ergonomics goals. Different macrohuman factors are considered while designing and formulating human work safety of such systems and one of the important neuroergonomic factors in is the Cognitive and Mental Workload (C-MWL). The mental workload (MWL) in the human’s brain is measured with difference non-invasive neuroimaging techniques. Most of the cognitive load measuring methods either require massive system protocols like fMRI (functional magnetic resonance imagining), positron-emission tomography (PET) or strict human anatomical movements restrictions like electroencephalogram (EEG) and magnetoencephalography (MEG). To address these limitations, fNIRS (functional Near infrared Spectroscopy) is used in this research to measure the hemodynamic changes in the human brain’s tissues as a measure of the brain activity. The brain’s hemodynamic signals are measured using a light weight portable fNIRS system (P-fNIRSSyst) that is designed to measure relative change in concentration of chromophores (oxy and deoxy hemoglobin) in brain tissues. In this study a novel variant of MBLL (Modified Beer-lambert Law) is designed by keeping the previous intensity value as a reference by taking the average from initial four seconds activity stimuli in optical density. The four second stimuli average in novel and important in calculation the changes in concentration of chromophores. This novel variant of MBLL is Fixed Value - Modified Beer-lambert Law (FV-MBLL). In this research, MWL is measured and classified in different real time working environments. The two-state cognitive load is measured with fNIRS system and classified using FV-MBLL using machine learning techniques like k-nearest neighbors (k-NN), support vector machines (SVM), and artificial neural networks (ANN). The classification accuracies of FV-MBLL are better than MBLL. The research further explores the classification capabilities of deep neural networks (DNN) such as convolutional neural network s (CNN) and Long short-term memory (LSTM) for the first time in assessment and classification of four- iv state MWL. The classification accuracies of LSTM outperform not only ML algorithms (SVM, KNN and ANN) but CNN as well in classification of multi-state MWL. The research experimental validation is performed using the accuracies with MWL that are further utilized in neurorehabilitation as neurofeedback to operate bionic systems using Brain Machine Interface (BMI). 30cm.

Place Hold on Fixed-Value MBLL based Cognitive Hemodynamic response assessment using P-fNIRS system: Applications to Deep Learning Brain Machine Interface (BMI) /

Integrative medical biochemistry : examination and board review /

By King, Michael W.. New York : McGraw-Hill Education, 2014 . xv, 892 pages : , Includes bibliographical references and index. 28 cm.. 9780071786126 (pbk. alk. paper)

Place Hold on Integrative medical biochemistry :

Essential surgical practice : higher surgical training in general surgery /

London ; | New York : Arnold, 2015 . xii, 1064 pages : 29 cm.. 9781444137620

Place Hold on Essential surgical practice :