NUST Institutions Library Catalogue

Includes index.

Section I – Fuel Metabolism
Metabolic Fuels and Dietary Components
The Fed or Absorptive State
Fasting.
Section II – Chemical and Biologic Foundations of Biochemistry
Water, Acids, Bases, and Buffers
Structures of the Major Compounds of the Body
Amino Acids in Proteins
Structure–Function Relationships in Proteins
Enzymes as Catalysts
Regulation of Enzymes
Relationship Between Cell Biology and Biochemistry
Cell Signaling by Chemical Messengers.
Section III – Gene Expression and the Synthesis of Proteins
Structure of the Nucleic Acids
Synthesis of DNA
Transcription: Synthesis of RNA
Translation: Synthesis of Proteins
Regulation of Gene Expression
Use of Recombinant DNA Techniques in Medicine
The Molecular Biology of Cancer.
Section IV – Fuel Oxidation and ATP Generation
Cellular Bioenergetics: ATP and O₂
Tricarboxylic Acid Cycle
Oxidative Phosphorylation and Mitochondrial Function
Generation of ATP from Glucose: Glycolysis
Oxidation of Fatty Acids and Ketone Bodies
Oxygen Toxicity and Free Radical Injury
Metabolism of Ethanol.
Section V – Carbohydrate Metabolism
Regulation of Fuel Metabolism by Hormones
Digestion, Absorption, and Transport of Carbohydrates
Formation and Degradation of Glycogen
Pentose Phosphate Pathway, Fructose, and Galactose Metabolism
Synthesis of Glycosides, Lactose, Glycoproteins, and Glycolipids
Gluconeogenesis and Blood Glucose Maintenance.
Section VI – Lipid Metabolism
Digestion and Transport of Dietary Lipids
Synthesis of Fatty Acids and Triacylglycerols
Cholesterol Metabolism and Fate
Metabolism of the Eicosanoids
Integration of Carbohydrate and Lipid Metabolism.
Section VII – Nitrogen Metabolism
Protein Digestion and Amino Acid Absorption
Fate of Amino Acid Nitrogen: Urea Cycle
Synthesis and Degradation of Amino Acids
Tetrahydrofolate, Vitamin B12, and SAM
Purine and Pyrimidine Metabolism
Intertissue Relationships in Amino Acid Metabolism.
Section VIII – Tissue Metabolism
Actions of Hormones Regulating Fuel Metabolism
Biochemistry of Erythrocytes and Other Blood Cells
Blood Plasma Proteins, Coagulation, and Fibrinolysis
Liver Metabolism
Muscle Metabolism During Rest and Exercise
Metabolism of the Nervous System
Extracellular Matrix and Connective Tissue
Appendix: Answers to Review Questions
Index.

Marks' Basic Medical Biochemistry: A Clinical Approach is a comprehensive medical biochemistry textbook that explains the biochemical processes of the human body through a clinically oriented approach. The book integrates fundamental concepts of molecular biology, enzymology, metabolism, genetics, and nutrition with real-life medical cases and disease correlations to help students understand the relationship between biochemistry and clinical medicine. It covers carbohydrate, lipid, protein, and nucleic acid metabolism; cellular communication; gene expression; energy production; hormonal regulation; and tissue-specific metabolism, while emphasizing the biochemical basis of disorders such as diabetes, cancer, inherited metabolic diseases, and cardiovascular conditions. Widely used by medical, dental, pharmacy, and allied health students, the text combines detailed illustrations, clinical examples, and review questions to support both foundational learning and exam preparation. Provided by publisher.

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