000			02027nam a22001577a 4500
082			_a610
100			_aArif, Wafa _9122616
245			_aAntibacterial Activity of Dental Composite integrated with Ciprofloxacin loaded Silver Nanoparticles / _cWafa Arif
264			_aIslamabad : _bSMME- NUST; _c2022.
300			_a68p. _bSoft Copy _c30cm
500			_aResin composites have been widely used in dental restoration. However, polymerization shrinkage and resultant bacterial microleakage is a major limitationthat may leads to secondary caries. To overcome this, a new type of antibacterial resincomposites containing ciprofloxacin loaded silver nanoparticles were synthesized. Ciprofloxacin loaded silver nanoparticles were successfully synthesized withchemical reduction method which was confirmed by Ultraviolet–visible (UV-Vis) spectroscopy, Scanning Electron Microscopy (SEM), Fourier-transforminfraredspectroscopy (FTIR) and Zeta potential. Ciprofloxacin loaded silver nanoparticles were added into resin composites. The antibacterial properties of these ciprofloxacinloaded silver nanoparticles modified resin composites against Enterococcus faecalis, Streptococcus mutans and Saliva Microcosm model were evaluated. Cytotoxicityof these modified resin composites was determined by performing hemolytic assay. Compressive strength (CS) of these modified resin composites was assessed byauniversal testing machine. The results indicated that the antibacterial activityandcompressive strength of resin composites containing Ciprofloxacin loaded silver nanoparticles were superior to the control group and also exhibited less cytotoxicityas compared to the resin composites containing silver nanoparticles. In short, theseresults established strong ground applications for CIP-AgNPs modified dental composite resins.
650			_aMS Biomedical Engineering (BME) _9119509
700			_aSupervisor : Dr. Nosheen Fatima Rana
856			_uhttp://10.250.8.41:8080/xmlui/handle/123456789/30725
942			_2ddc _cTHE
999			_c609071 _d609071