000			01724nam a22001577a 4500
082			_a610
100			_aRiaz, Aqsa _9121483
245			_aComplex Materialsfor Skin Diseases / _cAqsa Riaz
264			_aIslamabad : _bSMME- NUST; _c2025.
300			_a65p. _bSoft Copy _c30cm
500			_aFor the development of complex multifunctional materials as advanced wound dressings for the treatment of skin diseases, particularly chronic and infected wounds. By integrating cerium oxide nanoparticles and thymol-based deep eutectic solvent hydrogels into a chitosan-gelatin matrix, the study addresses pressing challenges in wound care, including antimicrobial resistance, limited drug stability, and poor localization at wound sites. Engineered hydrogels provide sustained release of active compounds, effectively disrupt biofilms from resistant bacteria such as Staphylococcus aureus and Escherichia coli, and deliver combined antimicrobial, antioxidant, and antiinflammatory effects. Laboratory evaluations demonstrated significant antibacterial activity, enhanced biofilm inhibition, and improved healing potential compared to conventional therapies. The results establish these materials as strong candidates for next generation wound dressings, with future research focused on optimizing formulation stability and validating in vivo safety. This work contributes to advancements in wound management by offering promising solutions for minimizing antimicrobial resistance and enhancing healing outcomes in chronic skin infections.
650			_aMS Biomedical Sciences (BMS)
700			_aSupervisor : Dr. Nosheen Fatima Rana
856			_uhttp://10.250.8.41:8080/xmlui/handle/123456789/55614
942			_2ddc _cTHE
999			_c615166 _d615166