000 02557nam a22001577a 4500
082 _a610
100 _aMansoor, Mariam
_9133095
245 _aAn Intelligent Framework for Real-Time PCG Classification and Cardiac Monitoring Using Machine Learning /
_cMariam Mansoor
264 _aIslamabad :
_bSMME- NUST;
_c2026.
300 _a103p.
_bSoft Copy
_c30cm
500 _aThe accurate and timely diagnosis of cardiovascular diseases, particularly valvular heart disorders, is essential for reducing morbidity and mortality. However, conventional auscultation remains limited by subjectivity, ambient noise, and an inability to record or analyse sounds. This thesis addresses these limitations through a two-fold contribution: the development of a wearable, high-fidelity digital auscultation system and the integration of a real-time, AI-assisted classification framework for automated diagnosis. The first part of the research presents a custom-designed wearable digital stethoscope using a piezoelectric contact sensor embedded in an aluminium chestpiece. This configuration offers superior acoustic coupling and environmental noise rejection. A multi-stage low-noise analog signal chain was designed, incorporating band-specific filtering to isolate heart and lung signals. A miniaturized PCB was fabricated to house the circuit, and a Python-based GUI was developed to visualize, record, and archive phonocardiogram (PCG) signals while generating patient-linked reports. In the second phase, a lightweight 1D convolutional neural network (CardioSynx) was introduced for real-time classification of five PCG classes, including normal and pathological valve conditions. The model trained offline using Butterworth filtering, Hilbert envelope segmentation, and wavelet denoising, achieved 97.5% ± 0.22 accuracy on validation data. For deployment, the system employed a parallel processing architecture to enable simultaneous audio acquisition, denoising, feature extraction, and inference, achieving a frame-level latency of 58 ms, well below clinical standards and an SNR of 16.8 dB. Real-time evaluation on patients yielded over 90% accuracy across key pathologies. Together, the proposed system delivers a scalable, real-time, and clinically robust platform for digital auscultation and decision support in modern healthcare.
650 _aMS Biomedical Engineering (BME)
_9119509
700 _aSupervisor: Dr Muhammad Asim Waris
_9119524
856 _uhttp://10.250.8.41:8080/xmlui/handle/123456789/57337
942 _2ddc
_cTHE
999 _c616088
_d616088