000			01762nam a22001577a 4500
082			_a610
100			_aAbbasi, Aliza Anwaar _9133194
245			_aNovel Bioactive Dental Fillings for Secondary Caries / _cAliza Anwaar Abbasi
264			_aIslamabad : _bSMME- NUST; _c2026.
300			_a64p. _bSoft Copy _c30cm
500			_aSecondary caries rests as the most important challenge in resin-based dental composites, encouraging search of bioactive fillers like silanized hydroxyapatites and fluorides to increase antibacterial performance without negotiating mechanical integrity. This study developed and verified novel UDMA-based composites: a control with camphorquinone photoinitiator, whereas the experimental group integrating APTES-silanized hydroxyapatite plus calcium fluoride. Antibacterial efficacy was evaluated via disk diffusion assays against Staphylococcus aureus and Escherichia coli, revealing clear zones of inhibition nearby experimental disks greater than controls representing fluoride-driven disruption of bacterial growth. Wide-ranging characterization, including SEM, FTIR, EDX analysis, water absorption and solubility done by the use of artificial saliva confirmed efficacious synthesis, structural integrity, and the existence of preferred functional groups. Outcomes highlight these formulations potential to limit oral biofilms and improve restorative durability, with silanization helping filler dispersion and ion release; future work should measure mechanical properties and continuing fluoride kinetics for medical translation.
650			_aMS Biomedical Sciences (BMS)
700			_aSupervisor: Dr. Sabah Javaid _9128370
856			_uhttp://10.250.8.41:8080/xmlui/handle/123456789/57400
942			_2ddc _cTHE
999			_c616199 _d616199